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Knowledge Base

Comprehensive guide to life extension technologies and interventions

Clinical Trials

Senolytic Therapies

Drugs that selectively eliminate senescent cells, reducing inflammation and improving tissue function

+3-7 years
dasatinibquercetinfisetin
Available Now

Rapamycin (mTOR Inhibition)

FDA-approved drug showing significant lifespan extension in animal models through mTOR pathway inhibition

+5-10 years
mTORautophagyoff-label
Available Now

Intermittent Fasting

Time-restricted eating patterns that trigger autophagy and metabolic improvements

+2-5 years
16:8OMADautophagy
Experimental

Gene Therapy

Direct genetic modifications to repair age-related damage and enhance longevity pathways

+10-20 years
CRISPRAAVtelomerase
Clinical Trials

Stem Cell Therapy

Regeneration of tissues and organs using pluripotent stem cells

+5-10 years
iPSCMSCregeneration
Available Now

Metformin

Diabetes drug showing promise for general longevity through metabolic regulation

+2-4 years
AMPKglucoseTAME trial
Available Now

NAD+ Boosters

Supplements that increase NAD+ levels, supporting cellular energy and DNA repair

+1-3 years
NMNNRniacin
Available Now

Exercise Optimization

Strategic mix of cardio, strength, and flexibility training for maximum healthspan

+3-7 years
HIITstrengthzone 2
Theoretical

Mind Uploading

Theoretical transfer of consciousness to digital substrates

Indefinite
consciousnessBCIemulation
Available Now

Cryonic Preservation

Ultra-low temperature preservation for future revival

Uncertain
vitrificationAlcorpreservation
Available Now

Caloric Restriction

Reducing calorie intake while maintaining nutrition to extend lifespan

+3-5 years
CRlongevity dietmetabolism
Experimental

Epigenetic Reprogramming

Resetting cellular age through Yamanaka factors and epigenetic modifications

+15-30 years
Yamanakamethylationrejuvenation

Evidence-Based Approach

All technologies in our knowledge base are rated based on scientific evidence, clinical trials, and real-world results. Always consult with healthcare professionals before starting any intervention.